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Single-shot two-dimensional full-range optical coherence tomography achieved by dispersion control

机译:色散控制实现的单次二维全范围光学相干断层扫描

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摘要

We present a full-range Fourier-domain optical coherence tomography (OCT) system that is capable of acquiring two-dimensional images of living tissue in a single shot. By using line illumination of the sample in combination with a two-dimensional imaging spectrometer, 1040 depth scans are performed simultaneously on a sub-millisecond timescale. Furthermore, we demonstrate an easy and flexible real-time single-shot technique for full-range (complex-conjugate cancelled) OCT imaging that is compatible with both two-dimensional as well as ultrahighresolution OCT. By implementing a dispersion imbalance between reference and sample arms of the interferometer, we eliminate the complex-conjugate signal through numerical dispersion compensation, effectively increasing the useful depth range by a factor of two. The system allows us to record 6.7 × 3.2 mm images at 5 μm depth resolution in 0.2 ms. Data postprocessing requires only 4 s. We demonstrate the capability of our system by imaging the anterior chamber of a mouse eye in vitro, as well as human skin in vivo. © 2009 Optical Society of America.
机译:我们提出了一种全范围的傅立叶域光学相干断层扫描(OCT)系统,该系统能够在单次拍摄中获取活组织的二维图像。通过结合使用样品的线照明和二维成像光谱仪,可以在亚毫秒级的时间范围内同时执行1040次深度扫描。此外,我们展示了一种用于全范围(复共轭消除)OCT成像的轻松,灵活的实时单发技术,该技术与二维和超高分辨率OCT均兼容。通过在干涉仪的参考臂和样本臂之间实现色散不平衡,我们通过数值色散补偿消除了复共轭信号,有效地将有用的深度范围扩大了两倍。该系统允许我们在0.2 ms内以5μm的深度分辨率记录6.7×3.2 mm的图像。数据后处理仅需4 s。我们通过在体外以及在人的皮肤上成像小鼠眼的前房来证明我们系统的功能。 ©2009美国眼镜学会。

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